Phage Display Platform
We have a premier antibody discovery and development platform that incorporates leading capabilities in antibody phage display, library construction, proprietary antibody humanization and affinity enhancement and Bacterial Cell Expression (BCE) technologies. BCE was a key breakthrough for the discovery and manufacturing of antibodies and other proteins. Over 60 pharmaceutical and biotechnology companies have signed licenses to XOMA's BCE technology.
The XOMA antibody platform is built as a combination of novel technologies and unique know-how. XOMA’s access to major commercial phage libraries provided us with special insight and knowledge to create top-performing custom libraries. Our novel expression-enhancing advancements improve the functional activity of our phage libraries. In addition, we have demonstrated that with optimized panning techniques we can maximize specific hits to cell-surface targets, including GPCRs, and help identify antibodies with unique modulatory function.