Phage Display Platform

XOMA has a premier antibody discovery and development platform that incorporates leading capabilities in antibody phage display, library construction, proprietary antibody humanization and affinity enhancement and Bacterial Cell Expression (BCE) technologies.

BCE was a key breakthrough for the discovery and manufacturing of antibodies and other proteins.

The XOMA antibody platform is built as a combination of novel technologies and unique know-how.  XOMA’s access to major commercial phage libraries provided us with special insight and knowledge to create top-performing custom libraries.  Our novel expression-enhancing advancements improve the functional activity of our phage libraries.  In addition, we have demonstrated that with optimized panning techniques, we can maximize specific hits to cell-surface targets, including G protein-coupled receptors (GPCRs), and help identify antibodies with unique modulatory function.